Product Name :DUSP7 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Dual specificity protein phosphatase . Shows high activity towards MAPK1/ERK2 . Also has lower activity towards MAPK14 and MAPK8 . In arrested oocytes, plays a role in meiotic resumption (By similarity). Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in oocytes, probably by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB (By similarity). May also inactivate PRKCA and/or PRKCG (By similarity). Also important in oocytes for normal chromosome alignment on the metaphase plate and progression to anaphase, where it might regulate activity of the spindle-assembly checkpoint (SAC) complex (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of DUSP7 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PYST2; Dual specificity protein phosphatase 7; Dual specificity protein phosphatase PYST2
Immunogen :A synthetic peptide encompassing a sequence within the center region of human DUSP7.
Modification :Unmodification
