Product Name :FAM102A polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Early estrogen-induced gene 1 protein: Key component of TNFSF11/RANKL- and TNF-induced osteoclastogenesis pathways, thereby mediates bone resorption in pathological bone loss conditions (By similarity). Required for TNFSF11/RANKL-induced osteoclastogenesis via its interaction with TNFRSF11A/RANK, thereby facilitates the downstream transcription of NFATC1 and activation of PLCG2 (By similarity). Facilitates recruitment of the transcriptional repressor PRDM1/BLIMP1 to the promoter of the anti-osteoclastogenesis gene IRF8, thereby resulting in transcription of osteoclast differentiation factors (By similarity). May play a role in estrogen action
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of FAM102A protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C9orf132; EEIG1; Protein FAM102A; Early estrogen-induced gene 1 protein
Immunogen :A synthetic peptide encompassing a sequence within the center region of human FAM102A.
Modification :Unmodification
