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MXRA8 polyclonal antibody

货号: BS35855

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS35855

Product Name :MXRA8 polyclonal antibody

Swiss-Prot :Q9BRK3

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Background :Matrix remodeling-associated protein 8: Transmembrane protein which can modulate activity of various signaling pathways, probably via binding to integrin ITGAV:ITGB3 . Mediates heterophilic cell-cell interactions in vitro (By similarity). Inhibits osteoclastogenesis downstream of TNFSF11/RANKL and CSF1, where it may function by attenuating signaling via integrin ITGB3 and MAP kinase p38 (By similarity). Plays a role in cartilage formation where it promotes proliferation and maturation of growth plate chondrocytes (By similarity). Stimulates formation of primary cilia in chondrocytes (By similarity). Enhances expression of genes involved in the hedgehog signaling pathway in chondrocytes, including the hedgehog signaling molecule IHH; may also promote signaling via the PTHLH/PTHrP pathway (By similarity). Plays a role in angiogenesis where it suppresses migration of endothelial cells and also promotes their apoptosis . Inhibi...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MXRA8 protein

BiowMW :~49.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Matrix-remodeling-associated protein 8; Limitrin

Immunogen :A synthetic peptide encompassing a sequence within the center region of human MXRA8.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PDGFR beta (Phospho-Y751) expression in THP1 EGF-treated (A), Raw264.7 EGF-treated (B), rat liver (C) whole cell lysates.

免疫沉淀（IP）