Product Name :LIN54 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)
Background :Protein lin-54 homolog: Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context . In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes . In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation . In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner . Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of LIN54 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CXCDC1; KIAA2037; Protein lin-54 homolog; CXC domain-containing protein 1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human LIN54.
Modification :Unmodification
