Product Name :DENND1A polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :DENN domain-containing protein 1A: Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes . Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of DENND1A protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :FAM31A; KIAA1608; DENN domain-containing protein 1A; Connecdenn 1; Connecdenn; Protein FAM31A
Immunogen :A synthetic peptide encompassing a sequence within the center region of human DENND1A.
Modification :Unmodification
