Product Name :IFFO1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Non-homologous end joining factor IFFO1: Nuclear matrix protein involved in the immobilization of broken DNA ends and the suppression of chromosome translocation during DNA double-strand breaks (DSBs) . Interacts with the nuclear lamina component LMNA, resulting in the formation of a nucleoskeleton that relocalizes to the DSB sites in a XRCC4-dependent manner and promotes the immobilization of the broken ends, thereby preventing chromosome translocation . Acts as a scaffold that allows the DNA repair protein XRCC4 and LMNA to assemble into a complex at the DSB sites
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of IFFO1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :IFFO; Intermediate filament family orphan 1; Tumor antigen HOM-TES-103
Immunogen :A synthetic peptide encompassing a sequence within the center region of human IFFO1.
Modification :Unmodification
