Product Name :KBTBD2 polyclonal antibody
Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)
Background :Kelch repeat and BTB domain-containing protein 2: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of the insulin signaling pathway, modulating insulin sensitivity by limiting PIK3R1/p85alpha abundance in adipocytes. Targets PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase (PI3K), for 'Lys-48'-linked polyubiquitination and proteasome-mediated degradation
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of KBTBD2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :BKLHD1; KIAA1489; Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human KBTBD2.
Modification :Unmodification
