Product Name :PLCD3 polyclonal antibody
Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)
Background :1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow . Regulates neurite outgrowth through the inhibition of RhoA/Rho kinase signaling (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of PLCD3 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA1964; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; Phosphoinositide phospholipase C-delta-3; Phospholipase C-delta-3; PLC-delta-3
Immunogen :A synthetic peptide encompassing a sequence within the center region of human PLCD3.
Modification :Unmodification
