Product Name :C7orf60 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :S-adenosylmethionine sensor upstream of mTORC1: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes . Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling . Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling . Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase (Potential)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of C7orf60 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Probable methyltransferase BTM2 homolog
Immunogen :A synthetic peptide encompassing a sequence within the center region of human C7orf60.
Modification :Unmodification
