Product Name :TRIM40 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :E3 ubiquitin ligase TRIM40: E3 ubiquitin-protein ligase that plays a role in the limitation of the innate immune response . Mediates inhibition of the RLR signaling pathway by ubiquitinating RIGI and IFIH1 receptors, leading to their proteasomal degradation . Also promotes the neddylation of IKBKG/NEMO, stabilizing NFKBIA, and thereby inhibiting of NF-kappa-B nuclear translocation and activation
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of TRIM40 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :RNF35; Tripartite motif-containing protein 40; Probable E3 NEDD8-protein ligase; RING finger protein 35
Immunogen :A synthetic peptide encompassing a sequence within the center region of human TRIM40.
Modification :Unmodification
