Product Name :HTR6 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :5-hydroxytryptamine receptor 6: G protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen . Also has a high affinity for tricyclic psychotropic drugs (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors . HTR6 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity . Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity). Is an activator of mTOR signaling
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of HTR6 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :5-hydroxytryptamine receptor 6; 5-HT-6; 5-HT6; Serotonin receptor 6
Immunogen :A synthetic peptide encompassing a sequence within the center region of human HTR6.
Modification :Unmodification
