Product Name :ZDHHC7 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Palmitoyltransferase ZDHHC7: Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes . Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity). Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane and their function in rapid intracellular signaling upon binding of sex hormones . Palmitoylates GNAQ, a heterotrimeric G protein, regulating its dynamic localization at the plasma membrane and is thereby involved in GNAQ-dependent G protein-coupled receptor signaling pathways . Also functions in ligand-induced cell death by regulating the FAS signaling pathway through the palmitoylation and...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ZDHHC7 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ZNF370; Palmitoyltransferase ZDHHC7; Zinc finger DHHC domain-containing protein 7; DHHC-7; Zinc finger protein 370
Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human ZDHHC7.
Modification :Unmodification
