Product Name :DHX37 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Probable ATP-dependent RNA helicase DHX37: ATP-binding RNA helicase that plays a role in maturation of the small ribosomal subunit in ribosome biogenesis . Required for the release of the U3 snoRNP from pre-ribosomal particles . Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome . Plays a role in early testis development . Probably also plays a role in brain development
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of DHX37 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DDX37; KIAA1517; Probable ATP-dependent RNA helicase DHX37; DEAH box protein 37
Immunogen :A synthetic peptide encompassing a sequence within the center region of human DHX37.
Modification :Unmodification
