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ATAT1 polyclonal antibody

货号: BS35261

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS35261

Product Name :ATAT1 polyclonal antibody

Swiss-Prot :Q5SQI0

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Alpha-tubulin N-acetyltransferase 1: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ATAT1 protein

BiowMW :~46.8 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C6orf134; MEC17; Alpha-tubulin N-acetyltransferase 1; Alpha-TAT; Alpha-TAT1; TAT; Acetyltransferase mec-17 homolog

Immunogen :A synthetic peptide encompassing a sequence within the center region of human ATAT1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of RBBP9 expression in LO2 (A), mouse kidney (B) whole cell lysates.

免疫沉淀（IP）