Product Name :PRICKLE3 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Prickle planar cell polarity protein 3: Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules, PRICKLE3 being part of the core module (By similarity). Distinct complexes of the core module segregate to opposite sides of the cell, where they interact with the opposite complex in the neighboring cell at or near the adherents junctions (By similarity). Involved in the organization of the basal body (By similarity). Involved in cilia growth and positioning (By similarity). Required for proper assembly, stability, and function of mitochondrial membrane ATP synthase (mitochondrial complex V)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of PRICKLE3 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :LMO6; Prickle-like protein 3; LIM domain only protein 6; LMO-6; Triple LIM domain protein 6
Immunogen :A synthetic peptide encompassing a sequence within the center region of human PRICKLE3.
Modification :Unmodification