Product Name :B3GNT7 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7: N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non-reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6-sulfoGlcNAcbeta)1->] within keratan sulfate polymer . Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency (By similarity) . May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of B3GNT7 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7; BGnT-7; Beta-1,3-Gn-T7; Beta-1,3-N-acetylglucosaminyltransferase 7; Beta3Gn-T7
Immunogen :A synthetic peptide encompassing a sequence within the center region of human B3GNT7.
Modification :Unmodification