Product Name :RRP1B polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Ribosomal RNA processing protein 1 homolog B: Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1 . Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus . Involved in regulation of mRNA splicing (By similarity). Inhibits SIPA1 GTPase activity (By similarity). Involved in regulating expression of extracellular matrix genes (By similarity). Associates with chromatin and may play a role in modulating chromatin structure
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of RRP1B protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0179; Ribosomal RNA processing protein 1 homolog B; RRP1-like protein B
Immunogen :A synthetic peptide encompassing a sequence within the center region of human RRP1B.
Modification :Unmodification