Product Name :SLC38A5 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Sodium-coupled neutral amino acid transporter 5: Symporter that cotransports neutral amino acids and sodium ions, coupled to an H(+) antiporter activity . Releases L-glutamine and glycine from astroglial cells and may participate in the glutamate/GABA-L-glutamine cycle and the NMDA receptors activation (By similarity). In addition, contributes significantly to L-glutamine uptake in retina, namely in ganglion and Mueller cells therefore, participates in the retinal glutamate-glutamine cycle (By similarity). The transport activity is pH sensitive and Li(+) tolerant . Moreover functions in both direction and is associated with large uncoupled fluxes of protons (By similarity). The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+) (By similarity). May have a particular importance for modulation of net hepatic glutamine flux (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SLC38A5 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :JM24; SN2; SNAT5; Sodium-coupled neutral amino acid transporter 5; Solute carrier family 38 member 5; System N transporter 2
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SLC38A5.
Modification :Unmodification