Product Name :RDH12 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Retinol dehydrogenase 12: Retinoids dehydrogenase/reductase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinal. Shows very weak activity towards 13-cis-retinol . Also exhibits activity, albeit with lower affinity than for retinaldehydes, towards lipid peroxidation products (C9 aldehydes) such as 4-hydroxynonenal and trans-2-nonenal . May play an important function in photoreceptor cells to detoxify 4-hydroxynonenal and potentially other toxic aldehyde products resulting from lipid peroxidation . Has no dehydrogenase activity towards steroids
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of RDH12 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Retinol dehydrogenase 12; All-trans and 9-cis retinol dehydrogenase
Immunogen :A synthetic peptide encompassing a sequence within the center region of human RDH12.
Modification :Unmodification
