Product Name :FBXO44 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :F-box only protein 44: Substrate-recognition component of two distinct E3 ligase complexes, the SKP1-CUL1-FBXO44 complex and the CUL4B-DDB1-FBXO44 complex . The complex SCF(FBXO44) complex ubiquitinates and mediates BRCA1 degradation . In association with cullin 4B/CUL4B and DDB1, mediates the ubiquitination of RGS2 leading to its degradation . Additionally, regulates the pregnane X receptor/NR1I2 protein level by ubiquitination and degradation
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of FBXO44 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :FBG3; FBX30; FBX44; FBX6A; FBXO6A; F-box only protein 44; F-box protein FBX30; F-box/G-domain protein 3
Immunogen :A synthetic peptide encompassing a sequence within the center region of human FBXO44.
Modification :Unmodification
