Product Name :POGLUT1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Protein O-glucosyltransferase 1: Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C . Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 . Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development . Notch glucosylation does not affect Notch ligand binding . Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of POGLUT1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C3orf9; CLP46; KTELC1; MDSRP; Protein O-glucosyltransferase 1; CAP10-like 46 kDa protein; hCLP46; KTEL motif-containing protein 1; Myelodysplastic syndromes relative protein
Immunogen :A synthetic peptide encompassing a sequence within the center region of human POGLUT1.
Modification :Unmodification
