Product Name :TYW1B polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B: Involved in the biosynthesis of wybutosine, a hyper modified guanosine with a tricyclic base located at position 37 of eukaryotic phenylalanine tRNA (tRNA(Phe)) that contributes to maintenance of the translational reading frame (By similarity). Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of TYW1B protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :RSAFD2; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; Radical S-adenosyl methionine and flavodoxin domain-containing protein 2; tRNA wybutosine-synthesizing protein 1 homolog B
Immunogen :A synthetic peptide encompassing a sequence within the center region of human TYW1B.
Modification :Unmodification
