Product Name :KIRREL3 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Kin of IRRE-like protein 3: Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons. May be involved in the hematopoietic supportive capacity of stroma cells; the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of KIRREL3 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA1867; NEPH2; Kin of IRRE-like protein 3; Kin of irregular chiasm-like protein 3; Nephrin-like protein 2
Immunogen :A synthetic peptide encompassing a sequence within the center region of human KIRREL3.
Modification :Unmodification