Product Name :CCDC115 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Vacuolar ATPase assembly protein VMA22: Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation . May be involved in Golgi homeostasis
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of CCDC115 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Coiled-coil domain-containing protein 115
Immunogen :A synthetic peptide encompassing a sequence within the center region of human CCDC115.
Modification :Unmodification