Product Name :C9orf142 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Protein PAXX: Non-essential DNA repair protein involved in DNA non-homologous end joining (NHEJ); participates in double-strand break (DSB) repair and V(D)J recombination . May act as a scaffold required for accumulation of the Ku heterodimer, composed of XRCC5/Ku80 and XRCC6/Ku70, at double-strand break sites and promote the assembly and/or stability of the NHEJ machinery . Involved in NHEJ by promoting the ligation of blunt-ended DNA ends . Together with NHEJ1/XLF, collaborates with DNA polymerase lambda (POLL) to promote joining of non-cohesive DNA ends . Constitutes a non-essential component of classical NHEJ: has a complementary but distinct function with NHEJ1/XLF in DNA repair . Able to restrict infection by herpesvirus 1 (HSV-1) via an unknown mechanism
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of C9orf142 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Uncharacterized protein C9orf142
Immunogen :A synthetic peptide encompassing a sequence within the center region of human C9orf142.
Modification :Unmodification
