Product Name :FCHO1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :F-BAR domain only protein 1: Functions in an early step of clathrin-mediated endocytosis . Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors. Involved in the regulation of T-cell poliferation and activation . Affects TCR clustering upon receptor triggering and modulates its internalization, playing a role in TCR-dependent T-cell activation
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of FCHO1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0290; FCH domain only protein 1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human FCHO1.
Modification :Unmodification
