Product Name :CHORDC1 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Cysteine and histidine-rich domain-containing protein 1: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2 . Proposed to act as co-chaperone for HSP90 . May play a role in the regulation of NOD1 via a HSP90 chaperone complex . In vitro, has intrinsic chaperone activity . This function may be achieved by inhibiting association of ROCK2 with NPM1 . Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling . Involved in stress response . Prevents tumorigenesis
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of CHORDC1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CHP1; Cysteine and histidine-rich domain-containing protein 1; CHORD domain-containing protein 1; CHORD-containing protein 1; CHP-1; Protein morgana
Immunogen :A synthetic peptide encompassing a sequence within the center region of human CHORDC1.
Modification :Unmodification
