Product Name :PREX2 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein: Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of PREX2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DEPDC2; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; P-Rex2; PtdIns(3,4,5)-dependent Rac exchanger 2; DEP domain-containing protein 2
Immunogen :A synthetic peptide encompassing a sequence within the center region of human PREX2.
Modification :Unmodification
