Product Name :WRAP73 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :WD repeat-containing protein WRAP73: The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology . Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis; may promote docking of RAB8A- and ARL13B-containing vesicles
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of WRAP73 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :WDR8; WD repeat-containing protein WRAP73; WD repeat-containing protein 8; WD repeat-containing protein antisense to TP73 gene
Immunogen :A synthetic peptide encompassing a sequence within the center region of human WRAP73.
Modification :Unmodification