Product Name :SPPL2C polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Signal peptide peptidase-like 2C: Sperm-specific intramembrane-cleaving aspartic protease (I-CLiP) that cleaves distinct tail-anchored proteins and SNARE proteins . In elongated spermatids, modulates intracellular Ca(2+) homeostasis by controlling PLN abundance through proteolytic cleavage (By similarity). During spermatogenesis, processes SNARE proteins and impacts vesicular trafficking which supports compartmental reorganization in maturating spermatids and may play a role in formation of the acrosome
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SPPL2C protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :IMP5; Signal peptide peptidase-like 2C; SPP-like 2C; SPPL2c; Intramembrane protease 5; IMP-5
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SPPL2C.
Modification :Unmodification
