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AKNA polyclonal antibody

货号: BS34711

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS34711

Product Name :AKNA polyclonal antibody

Swiss-Prot :Q7Z591

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Microtubule organization protein AKNA: Centrosomal protein that plays a key role in cell delamination by regulating microtubule organization (By similarity). Required for the delamination and retention of neural stem cells from the subventricular zone during neurogenesis (By similarity). Also regulates the epithelial-to-mesenchymal transition in other epithelial cells (By similarity). Acts by increasing centrosomal microtubule nucleation and recruiting nucleation factors and minus-end stabilizers, thereby destabilizing microtubules at the adherens junctions and mediating constriction of the apical endfoot (By similarity). In addition, may also act as a transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development . Binds to A/T-rich promoters . It is unclear how it can both...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of AKNA protein

BiowMW :~155 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KIAA1968; AT-hook-containing transcription factor

Immunogen :A synthetic peptide encompassing a sequence within the center region of human AKNA.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Serpin A8 expression in mouse liver (A), rat liver (B) whole cell lysates.

免疫沉淀（IP）