Product Name :KIAA0430 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Meiosis regulator and mRNA stability factor 1: Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of KIAA0430 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :LKAP; MARF1; Meiosis arrest female protein 1; Limkain-b1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human KIAA0430.
Modification :Unmodification