Product Name :THG1L polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Probable tRNA(His) guanylyltransferase: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis (Probable). Also functions as a guanyl-nucleotide exchange factor/GEF for the MFN1 and MFN2 mitofusins thereby regulating mitochondrial fusion . By regulating both mitochondrial dynamics and bioenergetic function, it contributes to cell survival following oxidative stress
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of THG1L protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ICF45; Probable tRNA(His) guanylyltransferase; Interphase cytoplasmic foci protein 45; tRNA-histidine guanylyltransferase
Immunogen :A synthetic peptide encompassing a sequence within the center region of human THG1L.
Modification :Unmodification
