Product Name :CLYBL polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Citramalyl-CoA lyase, mitochondrial: Mitochondrial enzyme required to detoxify vitamin B12-poisoning metabolites . Acts as a citramalyl-CoA lyase by converting citramalyl-CoA into acetyl-CoA and pyruvate in the C5-dicarboxylate catabolism pathway, a pathway required to detoxify itaconate, a vitamin B12-poisoning metabolite . Also acts as a malyl-CoA thioesterase to detoxify malyl-CoA, a side product of citric acid cycle enzymes, which is toxic for the vitamin B12-dependent enzyme MMUT . Also acts as a malate synthase in vitro, converting glyoxylate and acetyl-CoA to malate . Also acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate . Also has very weak citramalate synthase activity in vitro
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of CLYBL protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CLB; Citrate lyase subunit beta-like protein, mitochondrial; Citrate lyase beta-like
Immunogen :A synthetic peptide encompassing a sequence within the center region of human CLYBL.
Modification :Unmodification
