Product Name :B3GALNT2 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2: Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of B3GALNT2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2; Beta-1,3-GalNAc-T2; Beta-1,3-N-acetylgalactosaminyltransferase II
Immunogen :A synthetic peptide encompassing a sequence within the center region of human B3GALNT2.
Modification :Unmodification
