Product Name :DLG5 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Disks large homolog 5: Acts as a regulator of the Hippo signaling pathway . Negatively regulates the Hippo signaling pathway by mediating the interaction of MARK3 with STK3/4, bringing them together to promote MARK3-dependent hyperphosphorylation and inactivation of STK3 kinase activity toward LATS1 . Positively regulates the Hippo signaling pathway by mediating the interaction of SCRIB with STK4/MST1 and LATS1 which is important for the activation of the Hippo signaling pathway. Involved in regulating cell proliferation, maintenance of epithelial polarity, epithelial-mesenchymal transition (EMT), cell migration and invasion . Plays an important role in dendritic spine formation and synaptogenesis in cortical neurons; regulates synaptogenesis by enhancing the cell surface localization of N-cadherin. Acts as a positive regulator of hedgehog (Hh) signaling pathway. Plays a critical role in the early point of...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of DLG5 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0583; PDLG; Disks large homolog 5; Discs large protein P-dlg; Placenta and prostate DLG
Immunogen :A synthetic peptide encompassing a sequence within the center region of human DLG5.
Modification :Unmodification
