Product Name :FBXO43 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :F-box only protein 43: Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation . Plays a vital role in modulating the ubiquitilation of CCNB1 and CDK1 during gametogenesis
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of FBXO43 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :EMI2; F-box only protein 43; Endogenous meiotic inhibitor 2
Immunogen :A synthetic peptide encompassing a sequence within the center region of human FBXO43.
Modification :Unmodification