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SLCO4A1 polyclonal antibody

货号: BS34627

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS34627

Product Name :SLCO4A1 polyclonal antibody

Swiss-Prot :Q96BD0

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Solute carrier organic anion transporter family member 4A1: Organic anion antiporter with apparent broad substrate specificity. Recognizes various substrates including thyroid hormones 3,3',5-triiodo-L-thyronine (T3), L-thyroxine (T4) and 3,3',5'-triiodo-L-thyronine (rT3), conjugated steroids such as estrone 3-sulfate and estradiol 17-beta glucuronide, bile acids such as taurocholate and prostanoids such as prostaglandin E2, likely operating in a tissue-specific manner . May be involved in uptake of metabolites from the circulation into organs such as kidney, liver or placenta. Possibly drives the selective transport of thyroid hormones and estrogens coupled to an outward glutamate gradient across the microvillous membrane of the placenta . The transport mechanism, its electrogenicity and potential tissue-specific counterions remain to be elucidated (Probable)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SLCO4A1 protein

BiowMW :~77.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :OATP1; OATP4A1; OATPE; SLC21A12; Solute carrier organic anion transporter family member 4A1; OATP4A1; Colon organic anion transporter; Organic anion transporter polypeptide-related protein 1; OATP-RP1; OATPRP1; POAT; Organic anion-transporting polypeptide E; OATP-E; Sodium-independent organic anion transporter E; Solute carrier family 21 member 12

Immunogen :A synthetic peptide encompassing a sequence within the center region of human SLCO4A1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of ASGPR2 expression in HepG2 (A) whole cell lysates.