Product Name :PDE9A polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP . Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart . Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of PDE9A protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
Immunogen :A synthetic peptide encompassing a sequence within the center region of human PDE9A.
Modification :Unmodification
