Product Name :ST6GALNAC1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1: Protein sialyltransferase specifically expressed in goblet cells that plays a key role in intestinal host-commensal homeostasis . Conjugates sialic acid with an alpha-2-6 linkage to N-acetylgalactosamine (GalNAc) glycan chains linked to serine or threonine in glycoproteins . Catalyzes the formation of the sialyl-Tn (S-Tn) antigen, an antigen found in intestinal goblet cells, as well as ulcerative colitis (UC) and various cancers . Protein sialylation in globlet cells is essential for mucus integrity and is required to protect the intestinal mucus against excessive bacterial proteolytic degradation
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ST6GALNAC1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :SIAT7A; Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; GalNAc alpha-2,6-sialyltransferase I; ST6GalNAc I; ST6GalNAcI; Sialyltransferase 7A; SIAT7-A
Immunogen :A synthetic peptide encompassing a sequence within the center region of human ST6GALNAC1.
Modification :Unmodification
