Product Name :SASS6 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Spindle assembly abnormal protein 6 homolog: Central scaffolding component of the centrioles ensuring their 9-fold symmetry (By similarity). Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells . Not required for centriole formation in embryonic stem cells but necessary to maintain centriole architecture (By similarity). Required for the recruitment of STIL to the procentriole and for STIL-mediated centriole amplification . Overexpression results in excess foci-bearing centriolar markers
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SASS6 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :SAS6; Spindle assembly abnormal protein 6 homolog; HsSAS-6
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SASS6.
Modification :Unmodification