Product Name :SLX1A/B polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Structure-specific endonuclease subunit SLX1: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SLX1A/B protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :GIYD1; SLX1; GIYD2; SLX1; Structure-specific endonuclease subunit SLX1; GIY-YIG domain-containing protein 1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SLX1A/B.
Modification :Unmodification
