Product Name :VPS8 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Vacuolar protein sorting-associated protein 8 homolog: Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations . Functions predominantly in APPL1-containing endosomes
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of VPS8 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0804; Vacuolar protein sorting-associated protein 8 homolog
Immunogen :A synthetic peptide encompassing a sequence within the center region of human VPS8.
Modification :Unmodification
