Product Name :FAM49B polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :CYFIP-related Rac1 interactor B: Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling . Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions. Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization . Protects against Salmonella bacterial infection. Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry . Also restricts infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes (By similarity). Involved in the regulation of mitochondrial dynamics and oxidative stress
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of FAM49B protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Protein FAM49B; L1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human FAM49B.
Modification :Unmodification
