Product Name :SMPDL3B polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Acid sphingomyelinase-like phosphodiesterase 3b: Lipid-modulating phosphodiesterase . Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (By similarity). Has in vitro phosphodiesterase activity, but the physiological substrate is unknown . Lacks activity with phosphocholine-containing lipids, but can cleave CDP-choline, and can release phosphate from ATP and ADP (in vitro) (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SMPDL3B protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ASML3B; Acid sphingomyelinase-like phosphodiesterase 3b; ASM-like phosphodiesterase 3b
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SMPDL3B.
Modification :Unmodification
