Product Name :TMEM41B polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Transmembrane protein 41B: Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes . Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine . Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted by ATG2 (ATG2A or ATG2B) to mediate autophagosome assembly . In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required . Required for normal motor neuron development (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of TMEM41B protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0033; Transmembrane protein 41B
Immunogen :A synthetic peptide encompassing a sequence within the center region of human TMEM41B.
Modification :Unmodification
