Product Name :FERMT1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Fermitin family homolog 1: Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of FERMT1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C20orf42; KIND1; URP1; Fermitin family homolog 1; Kindlerin; Kindlin syndrome protein; Kindlin-1; Unc-112-related protein 1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human FERMT1.
Modification :Unmodification