Product Name :SRP68 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Signal recognition particle subunit SRP68: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) . The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER . The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER . Binds the signal recognition particle RNA (7SL RNA), SRP72 binds to this complex subsequently . The SRP complex possibly participates in the elongation arrest function (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SRP68 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Signal recognition particle subunit SRP68; SRP68; Signal recognition particle 68 kDa protein
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SRP68.
Modification :Unmodification
