Product Name :SEC61G polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Protein transport protein Sec61 subunit gamma: Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER) (By similarity). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides (By similarity). The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex . The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SEC61G protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Protein transport protein Sec61 subunit gamma
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SEC61G.
Modification :Unmodification