Product Name :TTLL11 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Tubulin polyglutamylase TTLL11: Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Preferentially mediates ATP-dependent polyglutamate long side-chain elongation over the initiation step of the polyglutamylation reaction. Preferentially modifies the alpha-tubulin tail over a beta-tail (By similarity). Required for CCSAP localization to both spindle and cilia microtubules . Promotes tubulin polyglutamylation which stimulates spastin/SPAST-mediated microtubule severing, thereby regulating microtubule functions (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of TTLL11 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C9orf20; Tubulin polyglutamylase TTLL11; Tubulin--tyrosine ligase-like protein 11
Immunogen :A synthetic peptide encompassing a sequence within the center region of human TTLL11.
Modification :Unmodification
